教师名录

司伟副教授博士生导师,硕士生导师
所在院系:医学装备系
办公室:机械楼 357
电话:
邮箱:wei.si@seu.edu.cn
个人简介

欢迎国内外优秀的本科生、研究生来课题组垂询体验(例如:竞赛、SRTP项目、毕业设计和攻读博士/硕士研究生学位等),课题组将为各位同学提供个性化的发展规划和优厚的助研津贴与绩效奖励,简历投递邮箱地址wei.si@seu.edu.cn

 

司伟博士,副教授,博导/硕导,医学装备系主任,江苏省优青、江苏省青托,5657威尼斯至善青年学者A/B层次),江苏省优秀博士学位论文和5657威尼斯优秀博士学位论文获得者,入选5657威尼斯优才培育计划,担任《MaterialsInternational(ISSN: 2668-5728)期刊助理编辑和《Bioengineering International(ISSN 2668-7119)期刊编委。获Nanotechnology期刊杰出审稿人奖、3M Nano国际会议最佳论文奖指导教师、“Electrophoresis” 期刊Reviewer CertificateIOP Trusted Reviewer“Journal of Polymer Science”期刊Reviewer Certificate、闵瑜校友奖励基金等。

主要研究方向:微纳尺度下的(1)机械操控及机器人技术、(2)流体动力学及传感器、(3)结构工艺设计及加工制造、(4)程序语言算法和三维建模与仿真。

教学方面:5657威尼斯第二届“杰出教学奖”教学新秀奖(学院唯一)5657威尼斯第28届青年教师授课竞赛二等奖(每年约前5%可入围)、首届5657威尼斯教师教学创新大赛三等奖、5657威尼斯三育人先进个人、本科招生工作先进个人,作为项目负责人承担校级教改项目2项,已发表教改论文3篇,参编江苏省高等学校重点教材《前沿制造技术》,担任5657威尼斯本科生班主任,担任5657威尼斯学习优秀生指导教师,担任本科生大类培养指导教师,担任机械创新设计大赛、铸造工艺大赛、CIMC“西门子杯中国智能制造挑战赛、本科生工程训练综合能力竞赛指导教师并获得国家级、省部级奖多项,所带的本科毕业设计获得5657威尼斯本科生优秀毕业设计(论文)团队称号,所带的多届本科生毕业设计论文获得机械学院优秀毕业设计论文,所带的本科生SRTP项目获得省级SRTP项目支持,所带的本科班级团支部获5657威尼斯磐石计划校级项目立项,团队的本科生、研究生多人次获得过国家奖学金、励志奖学金等。

科研方面:Journal of the American Chemical SocietyACS Nano等国内外期刊发表SCI论文57篇,其中以第一作者和通讯作者在ACS NanoSmallSmall Methods等国内外期刊发表SCI论文32(包括IF>10.0SCI论文6篇,封面论文4),申请和授权发明专利22项。近年来作为主持人承担国家重点研发计划课题、国家自然科学基金面上项目、国家自然科学青年基金、江苏省基础研究计划(自然科学基金)优秀青年基金、江苏省基础研究计划(自然科学基金)青年基金、江苏省科协青年科技人才托举工程资助项目、南京市留学人员科技创新项目、江苏省仪器仪表学会智能医疗器械创新基金和校企合作基金等多个项目;作为参与人参加研究国家重点研发计划项目1项,国家自然科学基金重点基金2项和面上基金3项。国际国内作大会报告14次,特邀报告6次。

个人学术主页1https://orcid.org/0000-0001-7285-058X  

个人学术主页2https://www.researchgate.net/profile/Wei-Si-4/research

五篇代表作(通讯作者论文加*

1.    Si, W.*;Yu, M.; Wu, G.;Chen,  C.; Sha, J.; Zhang, Y.; Chen, Y.,A Nanoparticle-DNA Assembled Nanorobot Powered by Charge-Tunable Quad-Nanopore System. ACS Nano 2020, 14(11),  15349-15360. (IF17.1)

2.    Si, W.; Aksimentiev, A.,Nanopore  Sensing of Protein Folding. ACSNano 2017,11 (7), 7091-7100. (IF17.1)

3.    Si, W. *; Zhang, Y.; Wu, G.;Kan, Y.; Zhang,  Y.; Sha, J.; Chen, Y.,Discrimination of Protein Amino Acid or Its Protonated  State at Single-Residue Resolution byGraphene Nanopores. Small 2019,15 (14), e1900036. (IF13.3)

4.    Si, W.*; Sun, Q.; Chen,  C.; Yu, M.; Sha, J.; Zhang, Y.; Kan, Y.;Chen, Y., Detergent-Assisted Braking  ofPeptide Translocation through a Single-Layer Molybdenum Disulfide  Nanopore. Small Methods 2020, 1900822.( (IF12.4,封面论文)

5.    Si, W.*; Zhu, Z.; Wu, G.;Zhang, Y.; Chen, Y.; Sha, J. Encoding Manipulation of DNA‐NanoparticleAssembled Nanorobot Using Independently Charged Array Nanopores. Small Methods2022, 6(8): e2200318. (IF12.4)

特邀报告情况:

1.    司伟微纳尺度下的机械设计基础理论及其应用,第三届全国机械设计青年学术论坛(2024,2024-04-122024-04-14,湖南省韶山市(大会特邀报告)

2.    司伟纳米孔内的流场力及其在纳米机器人驱动中的应用,首届力学交叉前沿研究论坛, 2023-4-212023-4-23,江苏省南京市(大会特邀报告)

3.    司伟基于纳通道的微纳米流体传感与驱动技术,第十六届全国压电和声波理论及器件应用研讨会, 2022-10-112022-10-14,江苏省南京市(大会特邀报告)

4.     司伟DNA过孔操控辅助下的纳米孔测序技术,第一届5657威尼斯先进传感与智能制造国际青年学者论坛,2021-10-292021-10-31,江苏省南京市(大会分会场主席、特邀报告)

5.     Si, W.Controlled translocation of DNA through solid-statenanopores for sequencing and manipulation Si, Wei 2021 Nanopore Weekly Meeting,2021-7-192021-7-19, online(大会特邀报告)

6.     司伟,纳米孔限域在基因类疾病诊疗中的应用,第四届青年科学家论坛——“微纳制造与微纳机器人技术2019614日-16日,黑龙江省哈尔滨工业大学。(大会特邀报告)


学习经历
工作经历

202104-至今 ,5657威尼斯,5657威尼斯,副教授,硕导/博导

201806-202103月,5657威尼斯,5657威尼斯,讲师,硕导

教授课程

1.机械设计基础(56学时,本科生课程)

2.设计原理与方法II48学时,本科生课程)

3.工程创新体验课(32学时,本科生课程)

4.微纳机电系统(全英文,48学时,本科生课程)

5.高等机构学32学时,研究生课程)


研究方向
微纳尺度下的(1)机械操控及机器人技术、(2)流体动力学及传感器、(3)结构工艺设计及加工制造、(4)程序语言算法和三维建模与仿真。
审稿期刊

1.    NanoLetters

2.    ACSNano

3.    Small

4.    SmallMethods

5.    AdvancedScience

6.    ChemicalScience

7.    ACSApplied Materials & Interfaces

8.    ACSSensors

9.    Nanoscale

10.  TheJournal of Physical Chemistry

11.  Nanotechnology

12.  ChemicalPhysics Letters

13.  Journalof Polymer Science

14.  Journalof Physics D-Applied Physics

15.  Journalof Physics-Condensed Matter

16.  Measurement

17.  Langmuir

18.  ModernPhysics Letters B

19.  PhysicaScripta

20.  Electrophoresis

21.  NewJournal of Physics

22.  AnalyticalBiochemistry

23.  ElectrochimicaActa

24.  ExpertReview of Proteomics

25.  Journalof Environmental Quality

26.  ChineseJournal of Chemistry

27.  Polymer

28.  Frontiersin Chemistry

29.  IETNanobiotechnology


学术兼职

1.MaterialsInternational(ISSN: 2668-5728)期刊助理编辑

2.《BioengineeringInternational(ISSN 2668-7119)期刊编委


获奖情况

1.    2024年5657威尼斯本科招生工作先进个人

2.    2024年度5657威尼斯优秀研究生导师团队 8/9

3.    2024Wiley威立中国开放科学高贡献作者奖

4.    2024年江苏省高校青蓝工程优秀教学团队6/6

5.    2024年5657威尼斯三育人先进个人

6.    2024Journal of Polymer Science ReviewerCertificate

7.    2024年5657威尼斯至善青年学者A层次)

8.    2023年5657威尼斯第二届“杰出教学奖”教学新秀奖(学院唯一)

9.    2023I0P trusted reviewer award

10.  2022Electrophoresis ReviewerCertificate

11.  2022年闵瑜校友奖励基金

12.  20223M Nano国际会议最佳学生论文奖指导教师

13.  2021年5657威尼斯第28届青年教师授课竞赛二等奖(每年约前5%可入围)

14.  2021年首届5657威尼斯教师教学创新大赛三等奖

15.  2021年5657威尼斯第三批“课程思政”校级示范课

16.  2020年5657威尼斯至善青年学者B层次)

17.  2020Nanotechnology期刊最佳审稿人奖

18.  2020年5657威尼斯优才培育计

19.  2019年5657威尼斯优才培育计

20.  2019年江苏省优秀博士学位论文

21.  2019年5657威尼斯优秀博士学位论文


论文著作

论文著作:

第一作者或通讯作者教学论文(通讯作者论文加*

1.    司伟*,工科专业课教学中课程思政与启发式教学的有机融合. 教书育人(高教论坛) 2021, 110-112.

2.    司伟*,工科专业课程中教师思政教学的意识培养与能力提升. 教书育人(高教论坛)2021, No.760, 45-47.

3.    司伟*,机械设计课堂中的启发式引导教学. 面向一流课程建设的机械原理课程内涵发展与质量提升 2021, 204-206.

第一作者或通讯作者SCI论文(通讯作者论文加*

1.    Si, W.*; Chen, H.; Lin, X.; Wu,G.; Zhao, J.; Sha, J. Actuation mechanism of a nanoscale drilling rig based onnested carbon nanotubes. Nanoscale 2024, 16, 10414-10427.

2.    Si, W.*; Chen, J.; Zhang, Z.;Wu, G.; Zhao, J.; Sha, J. Electroosmotic Sensing of Uncharged Peptides andDifferentiating Their Phosphorylated States Using Nanopores. Chemphyschem 2024,25, e202400281.

3.    Lin,X.; Chen, H.; Wu, G.; Zhao, J.; Zhang, Y.; Sha, J.; Si, W.* Selective Capture and Manipulation of DNA throughDouble Charged Nanopores. J. Phys. Chem. Lett. 2024, 15, 5120-5129.

4.    Zhang,Z.; Wang, L.; Si, W.*Electroosmotic Flow-Driven DNA-CNT Nanomotor via Tunable Surface-ChargedNanopore Array. J. Phys. Chem. Lett. 2024, 15, 10950-10957.

5.    Zhang,Z.; Wu, G. S.; Zhang, Y.; Sha, J. J.; Si,W.* Amino Acid Sorting Based on Bifurcated Nanochannels with TunableSurface Charge. Adv. Theory Simul. 2024, 7, 2301251.

6.    Si, W.*; Zhang, Z.; Chen, J.;Wu, G.; Zhang, Y.; Sha, J., Protein Deceleration and Sequencing UsingSi(3)N(4)-CNT Hybrid Nanopores. Chemphyschem 2024, 25 (7), e202300866.

7.    Yuan,R.; Zhang, Z.; Wu, G.; Zhang, Y.; Sha, J.; Chen, Y.; Si, W.*, Unfolding of protein usingMoS(2)/SnS(2)heterostructure for nanopore-based sequencing. Nanotechnology2024, 35 (13), 135501.

8.    Si, W.*; Wang, L.; Lin, X.; Wu,G.; Zhang, Y.; Sha, J. A controllable nanoscale telescopic arm designed byencoding the nested multi-walled carbon nanotubes. Phys. Chem. Chem. Phys.2023, 25, 11805-11815.

9.    Ma,C.; Xu, W.; Liu, W.; Xu, C.; Si, W.*;Sha, J. Precise control of CNT-DNA assembled nanomotor using oppositely chargeddual nanopores. Nanoscale 2023, 15, 11052-11063.

10.  Si, W.*; Lin, X.; Wang, L.; Wu,G.; Zhang, Y.; Chen, Y.; Sha, J. Nanopore actuation of a DNA-trackednanovehicle. Nanoscale 2023, 15, 14659-14668.

11.  Si, W.*; Zhu, Z.; Wu, G.;Zhang, Y.; Chen, Y.; Sha, J. Encoding Manipulation of DNA‐NanoparticleAssembled Nanorobot Using Independently Charged Array Nanopores. Small Methods 2022,6(8): e2200318.

12.  Si, W.*; Yuan, R.; Wu, G.; Kan,Y.; Sha, J.; Chen, Y.; Zhang, Y.; Shen, Y. Navigated Delivery of Peptide to theNanopore Using In-Plane Heterostructures of MoS2 and SnS2 for ProteinSequencing. J. Phys. Chem. Lett. 2022, 3863-3872.

13.  Yu,M. #; Si, W. *##并列一作); Zeng, T. #; Chen, C.; Lin, X.;Ji, Z.; Guo, F.; Li, Y.; Sha, J.; Dong, Y. Unveiling the Microscopic Mechanismof Current Variation in the Sensing Region of the MspA Nanopore for DNASequencing. J. Phys. Chem. Lett. 2021, 12(37): 9132-9141.

14.  Si, W.*; Yang, H.; Wu, G.;Zhang, Y.; Sha, J. Velocity control of protein translocation through a nanoporeby tuning the fraction of benzenoid residues. Nanoscale 2021, 13(36):15352-15361.

15.  Si, W.*; Chen, C.; Wu, G.; Sun,Q.; Yu, M.; Qiao, Y.; Sha, J. High Efficient Seawater Desalination Based onParallel Nanopore Systems. Nano 2021, 16, 2150077.

16.  Si, W.*;Yu, M.; Wu, G.;Chen,  C.; Sha, J.; Zhang, Y.; Chen, Y.,A Nanoparticle-DNA Assembled Nanorobot Powered by Charge-Tunable Quad-Nanopore System. ACS Nano 2020, 14 (11),  15349-15360.

17.  Si, W.*; Sun, Q.; Chen,  C.; Yu, M.; Sha, J.; Zhang, Y.; Kan, Y.;Chen, Y., Detergent-Assisted Braking  ofPeptide Translocation through a Single-Layer Molybdenum Disulfide  Nanopore. Small Methods 2020, 1900822.(封面论文)

18.  Si, W.*; Yang, H.;  Wu, G.; Chen, C.; Yu, M., Manipulation of DNAtransport through solid-state  nanoporesby atomic force microscopy. Materials Research Express 2020,7 (9), 095404.

19.  Liu,C. #; Si, W. ##并列一作); Wu, C.#; Yang, J.;  Chen, Y.; Dames, C., The ignored effects ofvibrational entropy and  electrocaloriceffect in PbTiO3 and PbZr0.5Ti0.5O3 as studied through  first-principles calculation. Acta Materialia2020,191,  221-229.

20.  Si, W.; Sha, J.; Sun, Q.; He,Z.; Wu, L.; Chen, C.; Yu,  S.-H.; Chen,Y., Shape Characterization and Discrimination of Single  Nanoparticles using Solid-state Nanopores.Analyst 2020,145 (5), 1657-1666. (封面论文)

21.  Si, W.*; Liu, C.; Sha, J.;Zhang, Y.; Chen, Y., Computational modeling of ionic currents through difform graphene nanopores withconsistent  cross-sectional areas. Phys.Chem. Chem. Phys. 2019,21  (47),26166-26174.

22.  Si, W. *; Zhang, Y.; Wu, G.;Kan, Y.; Zhang,  Y.; Sha, J.; Chen, Y.,Discrimination of Protein Amino Acid or Its Protonated  State at Single-Residue Resolution byGraphene Nanopores. Small 2019,15 (14), e1900036.

23.  Si, W.; Yang, H.; Sha, J.;Zhang,  Y.; Chen, Y., Discrimination ofsingle-stranded DNA homopolymers by sieving out G-quadruplex using tiny solid-state nanopores. Electrophoresis2019,40 (16-17), 2117-2124.(封面论文)

24.  Si, W. *; Zhang, Y.; Sha, J. J.;Chen, Y.  F., Mechanisms of pressure-inducedwater infiltration process through graphene nanopores. Mol Simulat 2019,45 (6), 518-524.

25.  Si, W.*; Zhang, Y.; Sha, J.;Chen, Y.,  Controllable and reversibleDNA translocation through a single-layer molybdenum disulfide nanopore. Nanoscale 2018,10 (41), 19450-19458.

26.  Sha,J.#; Si, W.##并列一作); Xu, B.; Zhang, S.; Li, K.; Lin, K.; Shi, H.; Chen, Y., Identificationof  Spherical and Nonspherical Proteinsby a Solid-State Nanopore. Anal. Chem. 2018,90 (23),  13826-13831.

27.  Si, W.; Yang, H. J.; Li, K.; Wu,  G. S.; Zhang, Y.; Kan, Y. J.; Xie, X.; Sha,J. J.; Liu, L.; Chen, Y. F., Investigation on the interaction length and access resistance of ananopore  with an atomic forcemicroscopy. Science  China-TechnologicalSciences 2017,60 (4), 552-560.

28.  Si, W.; Aksimentiev, A.,Nanopore  Sensing of Protein Folding. ACSNano 2017,11 (7), 7091-7100.

29.  Si, W.; Aksimentiev, A.,Nanopore  Ionic Current can Report on theFolding State of a Protein. Biophys. J. 2017,112 (3),  195a-195a.

30.  Cressiot,B.#; Greive, S. J.#; Si, W#.#并列一作); Pascoa, T. C.; Mojtabavi,M.;  Chechik, M.; Jenkins, H. T.; Lu, X.;Zhang, K.; Aksimentiev, A.; Antson, A. A.; Wanunu, M., Porphyrin-Assisted Docking of a Thermophage Portal Protein  into Lipid Bilayers: Nanopore Engineering andCharacterization. ACS Nano 2017,11 (12), 11931-11945.

31.  Si, W.; Zhang, Y.; Wu, G. S.;Sha,  J. J.; Liu, L.; Chen, Y. F., DNAsequencing technology based on nanopore sensors by theoretical calculations and simulations. Chinese ScienceBulletin 2014,59 (35), 4929-4941.

32.  Si, W.; Sha, J. J.; Liu, L.;Qiu,  Y. H.; Chen, Y. F., Effect ofnanopore size on poly(dT)(30) translocation through silicon nitride membrane. Sci. China: Technol. Sci. 2013,56 (10), 2398-2402.

 

其他SCI论文

33.  Lv,H.; Si, W.; Sha, J.; Chen,Y.; Zhang, Y. Strategies for high performance characterization of nanomaterialsusing in situ liquid cell transmission electron microscopy. Next Nanotechnology2025, 7, 100115.

34.  Zhang,Y.; Lian, X.; Si, W.; Sha,J.; Chen, Y. The origin of the voltage dependence of conductance blockades fromDNA translocation through solid-state nanopores. Materials Chemistry Frontiers2023, 7, 4564-4572.

35.  Sarthak,K.; Si, W.; Wilson, J.;Aksimentiev, A. Single-molecule identification of folded proteins from nanoporeionic current signatures. Biophys. J. 2023, 122, 156a-157a.

36.  Zhang,Z.; Chen, M.; Zhan, L.; Zheng, F.; Si,W.; Sha, J.; Chen, Y. Length-Dependent Collective Vibrational Dynamicsin Alpha-Helices. Chemphyschem 2022, 23, e202200082.

37.  Zhan,L.; Zhang, Y.; Si, W.; Sha,J.; Chen, Y. Detection and Separation of Single-Stranded DNA Fragments UsingSolid-State Nanopores. J. Phys. Chem. Lett. 2021, 12, 6469-6477.

38.  Zhang,Y.; Zhao, J.; Si, W.; Kan,Y.; Xu, Z.; Sha, J.; Chen, Y. Electroosmotic Facilitated Protein Capture andTransport through Solid‐State Nanopores with Diameter Larger than Length. SmallMethods 2020, 4, 1900893.

39.  Zhang,Y.; Zhao, J.; Kan, Y.; Ji, R.; Pan, J.; Huang, W.; Xu, Z.; Si, W.; Sha, J. Concentration effects on capture rate andtranslocation configuration of nanopore-based DNA detection. Electrophoresis2020, 41, 1523-1528.

40.  Wilson,J.; Sarthak, K.; Si, W.; Gao,L.; Aksimentiev, A. Rapid and Accurate Determination of Nanopore Ionic CurrentUsing a Steric Exclusion Model. ACS Sens 2019, 4, 634-644.

41.  Ma,J.; Li, K.; Li, Z.; Qiu, Y.; Si, W.;Ge, Y.; Sha, J.; Liu, L.; Xie, X.; Yi, H.; Ni, Z.; Li, D.; Chen, Y. DrasticallyReduced Ion Mobility in a Nanopore Due to Enhanced Pairing and Collisionsbetween Dehydrated Ions. J. Am. Chem. Soc. 2019, 141, 4264-4272.

42.  Yang,H.; Li, Z.; Si, W.; Lin, K.;Ma, J.; Li, K.; Sun, L.; Sha, J.; Chen, Y. Identification of Single Nucleotidesby a Tiny Charged Solid-State Nanopore. J. Phys. Chem. B 2018, 122, 7929–7935.

43.  Winogradoff,D.; Maffeo, C.; Si, W.;Aksimentiev, A. All-Atom Structure and Ionic Conductivity of the Nuclear PoreComplex. Biophys. J. 2018, 114, 630a-630a.

44.  Shi,X.; Li, Q.; Gao, R.; Si, W.;Liu, S. C.; Aksimentiev, A.; Long, Y. T. Dynamics of a Molecular Plug Dockedonto a Solid-State Nanopore. J. Phys. Chem. Lett. 2018, 9, 4686-4694.

45.  Zhang,Y.; Wu, G.; Si, W.; Ma, J.;Yuan, Z.; Xie, X.; Liu, L.; Sha, J.; Li, D.; Chen, Y. Ionic current modulationfrom DNA translocation through nanopores under high ionic strength andconcentration gradients. Nanoscale 2017, 9, 930-939.

46.  Yang,H. J.; Li, Z. W.; Chen, Y. F.; Si, W.Identification of Single Nucleotides in SiN Nanopore. Biophys. J. 2017, 112,25a-25a.

47.  Wolfe,A. J.; Si, W.; Zhang, Z.;Blanden, A. R.; Hsueh, Y. C.; Gugel, J. F.; Pham, B.; Chen, M.; Loh, S. N.; Rozovsky,S.; Aksimentiev, A.; Movileanu, L. Quantification of Membrane Protein-DetergentComplex Interactions. J. Phys. Chem. B 2017, 121, 10228-10241.

48.  Shi,X.; Gao, R.; Ying, Y. L.; Si, W.;Chen, Y. F.; Long, Y. T. A Scattering Nanopore for Single Nanoentity Sensing.Acs Sensors 2016, 1, 1086-1090.

49.  Cao,Y.; Lin, Y.; Qian, R. C.; Ying, Y. L.; Si,W.; Sha, J.; Chen, Y.; Long, Y. T. Evidence of single-nanoparticletranslocation through a solid-state nanopore by plasmon resonance energytransfer. Chem. Commun. (Camb.) 2016, 52, 5230-3.

50.  Shi,X.; Gao, R.; Ying, Y. L.; Si, W.;Chen, Y.; Long, Y. T. An integrated system for optical and electrical detectionof single molecules/particles inside a solid-state nanopore. Faraday Discuss.2015, 184, 85-99.

51.  Sha,J. J.; Si, W.; Xu, W.; Zou,Y. R.; Chen, Y. F. Glass capillary nanopore for single molecule detection.Science China-Technological Sciences 2015, 58, 803-812.

52.  Qiu,Y. H.; Li, K.; Chen, W. Y.; Si, W.;Tan, Q. Y.; Chen, Y. F. Ion and water transport in charge-modified graphenenanopores. Chinese Physics B 2015, 24, 108201.

53.  Kan,Y.; Tan, Q.; Wu, G.; Si, W.;Chen, Y. Study of DNA adsorption on mica surfaces using a surface forceapparatus. Sci. Rep. 2015, 5, 8442.

54.  Zhang,Y.; Wu, G. S.; Si, W.; Sha,J. J.; Liu, L.; Chen, Y. F. Retarding and manipulating of DNA moleculestranslocation through nanopores. Chin. Sci. Bull. 2014, 59, 4908-4917.

55.  Zhang,Y.; Wu, G.; Ma, J.; Yuan, Z.; Si, W.;Liu, L.; Sha, J.; Chen, Y. Temperature effect on translocation speed andcapture rate of nanopore-based DNA detection. Sci China Technol Sc 2014, 58,519-525.

56.  Wu,G. S.; Zhang, Y.; Si, W.;Sha, J. J.; Liu, L.; Chen, Y. F. Integrated solid-state nanopore devices forthird generation DNA sequencing. Science China-Technological Sciences 2014, 57,1925-1935.

57.  Qiu,Y. H.; Tan, Q. Y.; Si, W.;Chen, Y. F. Ion specificity in NaCl solution confined in silicon nanochannels.Science China-Technological Sciences 2014, 57, 230-238.


科研项目

作为负责人主持的纵向项目情况:

1.     2024/12-20227/11超灵敏纳米孔单分子传感器优化设计(国家重点研发计划课题,主持

2.     2023/01-2026/12基于纳米孔阵列的编码式纳米机器人驱动与操控关键技术研究(国家自然科学基金面上项目,主持

3.     2020/01-2022/12集成纳米机器人的蛋白质折叠密码破译芯片设计与制造的基础理论研究(国家自然科学基金青年基金,主持

4.     2023/09-2026/08纳米疗车机器人设计制造的关键技术研究(江苏省基础研究计划优秀青年基金项目,主持

5.     2019/07-2022/06基于纳米操控技术和纳米孔传感的蛋白质折叠病诊疗芯片研制的基础理论研究(江苏省基础研究计划青年基金项目,主持

6.     2023/07-2025/06江苏省科协青年科技人才托举工程——司伟资助培养(江苏省科协,主持

7.     2020/01-2021/12内嵌纳米机械手的蛋白质构象病即时诊疗芯片研制的关键技术(南京市2019年度留学人员科技创新项目,主持

8.     2020/01-2020/12纳米机器人技术在老年痴呆症等蛋白质构象病诊疗中的应用(江苏省仪器仪表协会面上基金,主持

作为负责人主持的横向项目情况:

9.     2023/12-2024/05螺钉自动送钉及锁付系统设计毕业设计合作协议(校企联合项目,主持

10.   2022/10-2023/10螺钉供料系统设计(校企联合项目,主持

11.   2020/03-2021/03孔蛋白虚拟筛选模型(校企联合项目,主持


专利

授权发明专利:

1.    司伟,林晓静,沙菁㛃,陈云飞。一种履带式纳米小车及其控制、制备方法。发明专利:ZL202210355100.020240709日。(授权)

2.    司伟,袁润逸,朱振东,沙菁㛃,陈云飞。二维平面异质结构的蛋白质拉伸测序平台及其制备方法。发明专利:ZL202110700951.X20230526日。(授权)

3.    章寅,赵佳斌,陈云飞,司伟,沙菁㛃。结合纳米孔技术的肿瘤标志miRNA检测装置及方法。发明专利:ZL201910680952 .520230228日。(授权)

4.    司伟,朱振东,袁润逸,沙菁㛃,陈云飞。一种编码式纳米机器及其控制、制备方法。发明专利:ZL202110700953.920221014日。(授权)

5.    沙菁㛃,刘巍,司伟,徐伟。DNA多足纳米移动装置及其驱动方法。发明专利:ZL202110270618.X20220628日。(授权)

6.    司伟,孙倩怡,陈畅,余梦,沙菁㛃,章寅,陈云飞。一种超灵敏塑胶炸弹侦测传感器。发明专利:ZL201911214153.520220304日。(授权)

7.    司伟,陈畅,孙倩怡,余梦,沙菁㛃,章寅,陈云飞。多自由度自组装纳米机器人及其制作控制方法。发明专利:ZL201911214317.42022517日。(授权)

8.    章寅,赵佳斌,董隽,陈云飞,司伟,沙菁㛃。一种外泌体内肿瘤标志miRNA的分离和检测系统及方法。发明专利:ZL201910064022.72022。(授权)

9.    沙菁㛃,张志诚,陈云飞,傅方舟,孙倩怡,司伟,章寅。一种基于激光诱导空化的纳尺度薄膜孔制备装置及其方法。发明专利:ZL201910270000.62021。(授权)

10.  沙菁㛃,孙倩怡,张志诚,傅方舟,陈云飞,司伟,章寅。一种光控纳米孔的单分子可控输出装置及其使用方法。发明专利:ZL201811186463.62020。(授权)

11.  沙菁㛃,张志诚,陈云飞,孙倩怡,傅方舟,司伟,章寅。纳米孔检测芯片的便携式装夹装置。发明专利:ZL201811328020.62019。(授权)

12.  陈云飞,司伟,伍根生,章寅,沙菁㛃,刘磊。一种多通道阵列式DNA测序系统及其测序方法。发明专利:ZL201410320550.12016。(授权)

13.  陈云飞,倪振华,邹益人,袁志山,赵伟玮,伍根生,徐伟,司伟,沙菁洁,刘磊。一种可控的二维材料柔性转移方法.发明专利:2015.5.28, ZL201510331341.12016。(授权)

14.  陈云飞,司伟,沙菁㛃,刘磊. 一种基于纳米孔和原子力显微镜的三通道并行DNA测序传感器及检测方法.发明专利:ZL201410084787.42015。(授权)

申请发明专利:

15.  司伟陈皓男陈云飞一种基于纳米管和磁珠的生物传感器及其制备方法和应用。202411271207.2,20241122日。(申请)

16.  司伟,何军舟。一种多壁碳纳米管的生物传感器及其制备方法与应用。发明专利:202411124761.8, 20241108日。(申请)

17.  司伟,陈皓男,沙菁㛃,陈云飞。一种纳米管嵌套钻机治疗装置及其控制、制备方法。发明专利:202310280299.X, 20230728日。(申请)

18.  吴金明,李天慧,司伟。利用曲柄滑块实现自转轴系无滑环输电的公转自转机构。发明专利:202410834059.4,20241015日。(申请)

19.  蔡路,司伟。一种基于纳米摩擦发电的转速传感器。发明专利:202310977665.7, 20230804日。(申请)

20.  司伟,张震,沙菁㛃,陈云飞。复合纳米孔生物传感器及其制备方法与应用。发明专利:202310303255.420230327日。(申请)

21.  沙菁㛃,马超凡,司伟,陈云飞,徐伟,刘巍,徐昌晖。一种电渗流驱动的纳米马达结构。发明专利:202310159496.62023。(申请)

22.  司伟,王立伟,沙菁㛃,陈云飞。一种纳米管嵌套伸缩式治疗装置及其控制、制备方法。发明专利:202210354772.X20220406日。(申请)


司伟 机器人技术、流体力学、程序算法、微纳传感
Tel:
Email:wei.si@seu.edu.cn
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Personal Introduction

欢迎国内外优秀的本科生、研究生来课题组垂询体验(例如:竞赛、SRTP项目、毕业设计和攻读博士/硕士研究生学位等),课题组将为各位同学提供个性化的发展规划和优厚的助研津贴与绩效奖励,简历投递邮箱地址wei.si@seu.edu.cn

 

司伟博士,副教授,博导/硕导,医学装备系主任,江苏省优青、江苏省青托,5657威尼斯至善青年学者A/B层次),江苏省优秀博士学位论文和5657威尼斯优秀博士学位论文获得者,入选5657威尼斯优才培育计划,担任《MaterialsInternational(ISSN: 2668-5728)期刊助理编辑和《Bioengineering International(ISSN 2668-7119)期刊编委。获Nanotechnology期刊杰出审稿人奖、3M Nano国际会议最佳论文奖指导教师、“Electrophoresis” 期刊Reviewer CertificateIOP Trusted Reviewer“Journal of Polymer Science”期刊Reviewer Certificate、闵瑜校友奖励基金等。

主要研究方向:微纳尺度下的(1)机械操控及机器人技术、(2)流体动力学及传感器、(3)结构工艺设计及加工制造、(4)程序语言算法和三维建模与仿真。

教学方面:5657威尼斯第二届“杰出教学奖”教学新秀奖(学院唯一)5657威尼斯第28届青年教师授课竞赛二等奖(每年约前5%可入围)、首届5657威尼斯教师教学创新大赛三等奖、5657威尼斯三育人先进个人、本科招生工作先进个人,作为项目负责人承担校级教改项目2项,已发表教改论文3篇,参编江苏省高等学校重点教材《前沿制造技术》,担任5657威尼斯本科生班主任,担任5657威尼斯学习优秀生指导教师,担任本科生大类培养指导教师,担任机械创新设计大赛、铸造工艺大赛、CIMC“西门子杯中国智能制造挑战赛、本科生工程训练综合能力竞赛指导教师并获得国家级、省部级奖多项,所带的本科毕业设计获得5657威尼斯本科生优秀毕业设计(论文)团队称号,所带的多届本科生毕业设计论文获得机械学院优秀毕业设计论文,所带的本科生SRTP项目获得省级SRTP项目支持,所带的本科班级团支部获5657威尼斯磐石计划校级项目立项,团队的本科生、研究生多人次获得过国家奖学金、励志奖学金等。

科研方面:Journal of the American Chemical SocietyACS Nano等国内外期刊发表SCI论文57篇,其中以第一作者和通讯作者在ACS NanoSmallSmall Methods等国内外期刊发表SCI论文32(包括IF>10.0SCI论文6篇,封面论文4),申请和授权发明专利22项。近年来作为主持人承担国家重点研发计划课题、国家自然科学基金面上项目、国家自然科学青年基金、江苏省基础研究计划(自然科学基金)优秀青年基金、江苏省基础研究计划(自然科学基金)青年基金、江苏省科协青年科技人才托举工程资助项目、南京市留学人员科技创新项目、江苏省仪器仪表学会智能医疗器械创新基金和校企合作基金等多个项目;作为参与人参加研究国家重点研发计划项目1项,国家自然科学基金重点基金2项和面上基金3项。国际国内作大会报告14次,特邀报告6次。

个人学术主页1https://orcid.org/0000-0001-7285-058X  

个人学术主页2https://www.researchgate.net/profile/Wei-Si-4/research

五篇代表作(通讯作者论文加*

1.    Si, W.*;Yu, M.; Wu, G.;Chen,  C.; Sha, J.; Zhang, Y.; Chen, Y.,A Nanoparticle-DNA Assembled Nanorobot Powered by Charge-Tunable Quad-Nanopore System. ACS Nano 2020, 14(11),  15349-15360. (IF17.1)

2.    Si, W.; Aksimentiev, A.,Nanopore  Sensing of Protein Folding. ACSNano 2017,11 (7), 7091-7100. (IF17.1)

3.    Si, W. *; Zhang, Y.; Wu, G.;Kan, Y.; Zhang,  Y.; Sha, J.; Chen, Y.,Discrimination of Protein Amino Acid or Its Protonated  State at Single-Residue Resolution byGraphene Nanopores. Small 2019,15 (14), e1900036. (IF13.3)

4.    Si, W.*; Sun, Q.; Chen,  C.; Yu, M.; Sha, J.; Zhang, Y.; Kan, Y.;Chen, Y., Detergent-Assisted Braking  ofPeptide Translocation through a Single-Layer Molybdenum Disulfide  Nanopore. Small Methods 2020, 1900822.( (IF12.4,封面论文)

5.    Si, W.*; Zhu, Z.; Wu, G.;Zhang, Y.; Chen, Y.; Sha, J. Encoding Manipulation of DNA‐NanoparticleAssembled Nanorobot Using Independently Charged Array Nanopores. Small Methods2022, 6(8): e2200318. (IF12.4)

特邀报告情况:

1.    司伟微纳尺度下的机械设计基础理论及其应用,第三届全国机械设计青年学术论坛(2024,2024-04-122024-04-14,湖南省韶山市(大会特邀报告)

2.    司伟纳米孔内的流场力及其在纳米机器人驱动中的应用,首届力学交叉前沿研究论坛, 2023-4-212023-4-23,江苏省南京市(大会特邀报告)

3.    司伟基于纳通道的微纳米流体传感与驱动技术,第十六届全国压电和声波理论及器件应用研讨会, 2022-10-112022-10-14,江苏省南京市(大会特邀报告)

4.     司伟DNA过孔操控辅助下的纳米孔测序技术,第一届5657威尼斯先进传感与智能制造国际青年学者论坛,2021-10-292021-10-31,江苏省南京市(大会分会场主席、特邀报告)

5.     Si, W.Controlled translocation of DNA through solid-statenanopores for sequencing and manipulation Si, Wei 2021 Nanopore Weekly Meeting,2021-7-192021-7-19, online(大会特邀报告)

6.     司伟,纳米孔限域在基因类疾病诊疗中的应用,第四届青年科学家论坛——“微纳制造与微纳机器人技术2019614日-16日,黑龙江省哈尔滨工业大学。(大会特邀报告)


Educational Background

论文著作:

第一作者或通讯作者教学论文(通讯作者论文加*

1.    司伟*,工科专业课教学中课程思政与启发式教学的有机融合. 教书育人(高教论坛) 2021, 110-112.

2.    司伟*,工科专业课程中教师思政教学的意识培养与能力提升. 教书育人(高教论坛)2021, No.760, 45-47.

3.    司伟*,机械设计课堂中的启发式引导教学. 面向一流课程建设的机械原理课程内涵发展与质量提升 2021, 204-206.

第一作者或通讯作者SCI论文(通讯作者论文加*

1.    Si, W.*; Chen, H.; Lin, X.; Wu,G.; Zhao, J.; Sha, J. Actuation mechanism of a nanoscale drilling rig based onnested carbon nanotubes. Nanoscale 2024, 16, 10414-10427.

2.    Si, W.*; Chen, J.; Zhang, Z.;Wu, G.; Zhao, J.; Sha, J. Electroosmotic Sensing of Uncharged Peptides andDifferentiating Their Phosphorylated States Using Nanopores. Chemphyschem 2024,25, e202400281.

3.    Lin,X.; Chen, H.; Wu, G.; Zhao, J.; Zhang, Y.; Sha, J.; Si, W.* Selective Capture and Manipulation of DNA throughDouble Charged Nanopores. J. Phys. Chem. Lett. 2024, 15, 5120-5129.

4.    Zhang,Z.; Wang, L.; Si, W.*Electroosmotic Flow-Driven DNA-CNT Nanomotor via Tunable Surface-ChargedNanopore Array. J. Phys. Chem. Lett. 2024, 15, 10950-10957.

5.    Zhang,Z.; Wu, G. S.; Zhang, Y.; Sha, J. J.; Si,W.* Amino Acid Sorting Based on Bifurcated Nanochannels with TunableSurface Charge. Adv. Theory Simul. 2024, 7, 2301251.

6.    Si, W.*; Zhang, Z.; Chen, J.;Wu, G.; Zhang, Y.; Sha, J., Protein Deceleration and Sequencing UsingSi(3)N(4)-CNT Hybrid Nanopores. Chemphyschem 2024, 25 (7), e202300866.

7.    Yuan,R.; Zhang, Z.; Wu, G.; Zhang, Y.; Sha, J.; Chen, Y.; Si, W.*, Unfolding of protein usingMoS(2)/SnS(2)heterostructure for nanopore-based sequencing. Nanotechnology2024, 35 (13), 135501.

8.    Si, W.*; Wang, L.; Lin, X.; Wu,G.; Zhang, Y.; Sha, J. A controllable nanoscale telescopic arm designed byencoding the nested multi-walled carbon nanotubes. Phys. Chem. Chem. Phys.2023, 25, 11805-11815.

9.    Ma,C.; Xu, W.; Liu, W.; Xu, C.; Si, W.*;Sha, J. Precise control of CNT-DNA assembled nanomotor using oppositely chargeddual nanopores. Nanoscale 2023, 15, 11052-11063.

10.  Si, W.*; Lin, X.; Wang, L.; Wu,G.; Zhang, Y.; Chen, Y.; Sha, J. Nanopore actuation of a DNA-trackednanovehicle. Nanoscale 2023, 15, 14659-14668.

11.  Si, W.*; Zhu, Z.; Wu, G.;Zhang, Y.; Chen, Y.; Sha, J. Encoding Manipulation of DNA‐NanoparticleAssembled Nanorobot Using Independently Charged Array Nanopores. Small Methods 2022,6(8): e2200318.

12.  Si, W.*; Yuan, R.; Wu, G.; Kan,Y.; Sha, J.; Chen, Y.; Zhang, Y.; Shen, Y. Navigated Delivery of Peptide to theNanopore Using In-Plane Heterostructures of MoS2 and SnS2 for ProteinSequencing. J. Phys. Chem. Lett. 2022, 3863-3872.

13.  Yu,M. #; Si, W. *##并列一作); Zeng, T. #; Chen, C.; Lin, X.;Ji, Z.; Guo, F.; Li, Y.; Sha, J.; Dong, Y. Unveiling the Microscopic Mechanismof Current Variation in the Sensing Region of the MspA Nanopore for DNASequencing. J. Phys. Chem. Lett. 2021, 12(37): 9132-9141.

14.  Si, W.*; Yang, H.; Wu, G.;Zhang, Y.; Sha, J. Velocity control of protein translocation through a nanoporeby tuning the fraction of benzenoid residues. Nanoscale 2021, 13(36):15352-15361.

15.  Si, W.*; Chen, C.; Wu, G.; Sun,Q.; Yu, M.; Qiao, Y.; Sha, J. High Efficient Seawater Desalination Based onParallel Nanopore Systems. Nano 2021, 16, 2150077.

16.  Si, W.*;Yu, M.; Wu, G.;Chen,  C.; Sha, J.; Zhang, Y.; Chen, Y.,A Nanoparticle-DNA Assembled Nanorobot Powered by Charge-Tunable Quad-Nanopore System. ACS Nano 2020, 14 (11),  15349-15360.

17.  Si, W.*; Sun, Q.; Chen,  C.; Yu, M.; Sha, J.; Zhang, Y.; Kan, Y.;Chen, Y., Detergent-Assisted Braking  ofPeptide Translocation through a Single-Layer Molybdenum Disulfide  Nanopore. Small Methods 2020, 1900822.(封面论文)

18.  Si, W.*; Yang, H.;  Wu, G.; Chen, C.; Yu, M., Manipulation of DNAtransport through solid-state  nanoporesby atomic force microscopy. Materials Research Express 2020,7 (9), 095404.

19.  Liu,C. #; Si, W. ##并列一作); Wu, C.#; Yang, J.;  Chen, Y.; Dames, C., The ignored effects ofvibrational entropy and  electrocaloriceffect in PbTiO3 and PbZr0.5Ti0.5O3 as studied through  first-principles calculation. Acta Materialia2020,191,  221-229.

20.  Si, W.; Sha, J.; Sun, Q.; He,Z.; Wu, L.; Chen, C.; Yu,  S.-H.; Chen,Y., Shape Characterization and Discrimination of Single  Nanoparticles using Solid-state Nanopores.Analyst 2020,145 (5), 1657-1666. (封面论文)

21.  Si, W.*; Liu, C.; Sha, J.;Zhang, Y.; Chen, Y., Computational modeling of ionic currents through difform graphene nanopores withconsistent  cross-sectional areas. Phys.Chem. Chem. Phys. 2019,21  (47),26166-26174.

22.  Si, W. *; Zhang, Y.; Wu, G.;Kan, Y.; Zhang,  Y.; Sha, J.; Chen, Y.,Discrimination of Protein Amino Acid or Its Protonated  State at Single-Residue Resolution byGraphene Nanopores. Small 2019,15 (14), e1900036.

23.  Si, W.; Yang, H.; Sha, J.;Zhang,  Y.; Chen, Y., Discrimination ofsingle-stranded DNA homopolymers by sieving out G-quadruplex using tiny solid-state nanopores. Electrophoresis2019,40 (16-17), 2117-2124.(封面论文)

24.  Si, W. *; Zhang, Y.; Sha, J. J.;Chen, Y.  F., Mechanisms of pressure-inducedwater infiltration process through graphene nanopores. Mol Simulat 2019,45 (6), 518-524.

25.  Si, W.*; Zhang, Y.; Sha, J.;Chen, Y.,  Controllable and reversibleDNA translocation through a single-layer molybdenum disulfide nanopore. Nanoscale 2018,10 (41), 19450-19458.

26.  Sha,J.#; Si, W.##并列一作); Xu, B.; Zhang, S.; Li, K.; Lin, K.; Shi, H.; Chen, Y., Identificationof  Spherical and Nonspherical Proteinsby a Solid-State Nanopore. Anal. Chem. 2018,90 (23),  13826-13831.

27.  Si, W.; Yang, H. J.; Li, K.; Wu,  G. S.; Zhang, Y.; Kan, Y. J.; Xie, X.; Sha,J. J.; Liu, L.; Chen, Y. F., Investigation on the interaction length and access resistance of ananopore  with an atomic forcemicroscopy. Science  China-TechnologicalSciences 2017,60 (4), 552-560.

28.  Si, W.; Aksimentiev, A.,Nanopore  Sensing of Protein Folding. ACSNano 2017,11 (7), 7091-7100.

29.  Si, W.; Aksimentiev, A.,Nanopore  Ionic Current can Report on theFolding State of a Protein. Biophys. J. 2017,112 (3),  195a-195a.

30.  Cressiot,B.#; Greive, S. J.#; Si, W#.#并列一作); Pascoa, T. C.; Mojtabavi,M.;  Chechik, M.; Jenkins, H. T.; Lu, X.;Zhang, K.; Aksimentiev, A.; Antson, A. A.; Wanunu, M., Porphyrin-Assisted Docking of a Thermophage Portal Protein  into Lipid Bilayers: Nanopore Engineering andCharacterization. ACS Nano 2017,11 (12), 11931-11945.

31.  Si, W.; Zhang, Y.; Wu, G. S.;Sha,  J. J.; Liu, L.; Chen, Y. F., DNAsequencing technology based on nanopore sensors by theoretical calculations and simulations. Chinese ScienceBulletin 2014,59 (35), 4929-4941.

32.  Si, W.; Sha, J. J.; Liu, L.;Qiu,  Y. H.; Chen, Y. F., Effect ofnanopore size on poly(dT)(30) translocation through silicon nitride membrane. Sci. China: Technol. Sci. 2013,56 (10), 2398-2402.

 

其他SCI论文

33.  Lv,H.; Si, W.; Sha, J.; Chen,Y.; Zhang, Y. Strategies for high performance characterization of nanomaterialsusing in situ liquid cell transmission electron microscopy. Next Nanotechnology2025, 7, 100115.

34.  Zhang,Y.; Lian, X.; Si, W.; Sha,J.; Chen, Y. The origin of the voltage dependence of conductance blockades fromDNA translocation through solid-state nanopores. Materials Chemistry Frontiers2023, 7, 4564-4572.

35.  Sarthak,K.; Si, W.; Wilson, J.;Aksimentiev, A. Single-molecule identification of folded proteins from nanoporeionic current signatures. Biophys. J. 2023, 122, 156a-157a.

36.  Zhang,Z.; Chen, M.; Zhan, L.; Zheng, F.; Si,W.; Sha, J.; Chen, Y. Length-Dependent Collective Vibrational Dynamicsin Alpha-Helices. Chemphyschem 2022, 23, e202200082.

37.  Zhan,L.; Zhang, Y.; Si, W.; Sha,J.; Chen, Y. Detection and Separation of Single-Stranded DNA Fragments UsingSolid-State Nanopores. J. Phys. Chem. Lett. 2021, 12, 6469-6477.

38.  Zhang,Y.; Zhao, J.; Si, W.; Kan,Y.; Xu, Z.; Sha, J.; Chen, Y. Electroosmotic Facilitated Protein Capture andTransport through Solid‐State Nanopores with Diameter Larger than Length. SmallMethods 2020, 4, 1900893.

39.  Zhang,Y.; Zhao, J.; Kan, Y.; Ji, R.; Pan, J.; Huang, W.; Xu, Z.; Si, W.; Sha, J. Concentration effects on capture rate andtranslocation configuration of nanopore-based DNA detection. Electrophoresis2020, 41, 1523-1528.

40.  Wilson,J.; Sarthak, K.; Si, W.; Gao,L.; Aksimentiev, A. Rapid and Accurate Determination of Nanopore Ionic CurrentUsing a Steric Exclusion Model. ACS Sens 2019, 4, 634-644.

41.  Ma,J.; Li, K.; Li, Z.; Qiu, Y.; Si, W.;Ge, Y.; Sha, J.; Liu, L.; Xie, X.; Yi, H.; Ni, Z.; Li, D.; Chen, Y. DrasticallyReduced Ion Mobility in a Nanopore Due to Enhanced Pairing and Collisionsbetween Dehydrated Ions. J. Am. Chem. Soc. 2019, 141, 4264-4272.

42.  Yang,H.; Li, Z.; Si, W.; Lin, K.;Ma, J.; Li, K.; Sun, L.; Sha, J.; Chen, Y. Identification of Single Nucleotidesby a Tiny Charged Solid-State Nanopore. J. Phys. Chem. B 2018, 122, 7929–7935.

43.  Winogradoff,D.; Maffeo, C.; Si, W.;Aksimentiev, A. All-Atom Structure and Ionic Conductivity of the Nuclear PoreComplex. Biophys. J. 2018, 114, 630a-630a.

44.  Shi,X.; Li, Q.; Gao, R.; Si, W.;Liu, S. C.; Aksimentiev, A.; Long, Y. T. Dynamics of a Molecular Plug Dockedonto a Solid-State Nanopore. J. Phys. Chem. Lett. 2018, 9, 4686-4694.

45.  Zhang,Y.; Wu, G.; Si, W.; Ma, J.;Yuan, Z.; Xie, X.; Liu, L.; Sha, J.; Li, D.; Chen, Y. Ionic current modulationfrom DNA translocation through nanopores under high ionic strength andconcentration gradients. Nanoscale 2017, 9, 930-939.

46.  Yang,H. J.; Li, Z. W.; Chen, Y. F.; Si, W.Identification of Single Nucleotides in SiN Nanopore. Biophys. J. 2017, 112,25a-25a.

47.  Wolfe,A. J.; Si, W.; Zhang, Z.;Blanden, A. R.; Hsueh, Y. C.; Gugel, J. F.; Pham, B.; Chen, M.; Loh, S. N.; Rozovsky,S.; Aksimentiev, A.; Movileanu, L. Quantification of Membrane Protein-DetergentComplex Interactions. J. Phys. Chem. B 2017, 121, 10228-10241.

48.  Shi,X.; Gao, R.; Ying, Y. L.; Si, W.;Chen, Y. F.; Long, Y. T. A Scattering Nanopore for Single Nanoentity Sensing.Acs Sensors 2016, 1, 1086-1090.

49.  Cao,Y.; Lin, Y.; Qian, R. C.; Ying, Y. L.; Si,W.; Sha, J.; Chen, Y.; Long, Y. T. Evidence of single-nanoparticletranslocation through a solid-state nanopore by plasmon resonance energytransfer. Chem. Commun. (Camb.) 2016, 52, 5230-3.

50.  Shi,X.; Gao, R.; Ying, Y. L.; Si, W.;Chen, Y.; Long, Y. T. An integrated system for optical and electrical detectionof single molecules/particles inside a solid-state nanopore. Faraday Discuss.2015, 184, 85-99.

51.  Sha,J. J.; Si, W.; Xu, W.; Zou,Y. R.; Chen, Y. F. Glass capillary nanopore for single molecule detection.Science China-Technological Sciences 2015, 58, 803-812.

52.  Qiu,Y. H.; Li, K.; Chen, W. Y.; Si, W.;Tan, Q. Y.; Chen, Y. F. Ion and water transport in charge-modified graphenenanopores. Chinese Physics B 2015, 24, 108201.

53.  Kan,Y.; Tan, Q.; Wu, G.; Si, W.;Chen, Y. Study of DNA adsorption on mica surfaces using a surface forceapparatus. Sci. Rep. 2015, 5, 8442.

54.  Zhang,Y.; Wu, G. S.; Si, W.; Sha,J. J.; Liu, L.; Chen, Y. F. Retarding and manipulating of DNA moleculestranslocation through nanopores. Chin. Sci. Bull. 2014, 59, 4908-4917.

55.  Zhang,Y.; Wu, G.; Ma, J.; Yuan, Z.; Si, W.;Liu, L.; Sha, J.; Chen, Y. Temperature effect on translocation speed andcapture rate of nanopore-based DNA detection. Sci China Technol Sc 2014, 58,519-525.

56.  Wu,G. S.; Zhang, Y.; Si, W.;Sha, J. J.; Liu, L.; Chen, Y. F. Integrated solid-state nanopore devices forthird generation DNA sequencing. Science China-Technological Sciences 2014, 57,1925-1935.

57.  Qiu,Y. H.; Tan, Q. Y.; Si, W.;Chen, Y. F. Ion specificity in NaCl solution confined in silicon nanochannels.Science China-Technological Sciences 2014, 57, 230-238.


Professional Experience

1.MaterialsInternational(ISSN: 2668-5728)期刊助理编辑

2.《BioengineeringInternational(ISSN 2668-7119)期刊编委


Teaching

作为负责人主持的纵向项目情况:

1.     2024/12-20227/11超灵敏纳米孔单分子传感器优化设计(国家重点研发计划课题,主持

2.     2023/01-2026/12基于纳米孔阵列的编码式纳米机器人驱动与操控关键技术研究(国家自然科学基金面上项目,主持

3.     2020/01-2022/12集成纳米机器人的蛋白质折叠密码破译芯片设计与制造的基础理论研究(国家自然科学基金青年基金,主持

4.     2023/09-2026/08纳米疗车机器人设计制造的关键技术研究(江苏省基础研究计划优秀青年基金项目,主持

5.     2019/07-2022/06基于纳米操控技术和纳米孔传感的蛋白质折叠病诊疗芯片研制的基础理论研究(江苏省基础研究计划青年基金项目,主持

6.     2023/07-2025/06江苏省科协青年科技人才托举工程——司伟资助培养(江苏省科协,主持

7.     2020/01-2021/12内嵌纳米机械手的蛋白质构象病即时诊疗芯片研制的关键技术(南京市2019年度留学人员科技创新项目,主持

8.     2020/01-2020/12纳米机器人技术在老年痴呆症等蛋白质构象病诊疗中的应用(江苏省仪器仪表协会面上基金,主持

作为负责人主持的横向项目情况:

9.     2023/12-2024/05螺钉自动送钉及锁付系统设计毕业设计合作协议(校企联合项目,主持

10.   2022/10-2023/10螺钉供料系统设计(校企联合项目,主持

11.   2020/03-2021/03孔蛋白虚拟筛选模型(校企联合项目,主持


Research Interests

授权发明专利:

1.    司伟,林晓静,沙菁㛃,陈云飞。一种履带式纳米小车及其控制、制备方法。发明专利:ZL202210355100.020240709日。(授权)

2.    司伟,袁润逸,朱振东,沙菁㛃,陈云飞。二维平面异质结构的蛋白质拉伸测序平台及其制备方法。发明专利:ZL202110700951.X20230526日。(授权)

3.    章寅,赵佳斌,陈云飞,司伟,沙菁㛃。结合纳米孔技术的肿瘤标志miRNA检测装置及方法。发明专利:ZL201910680952 .520230228日。(授权)

4.    司伟,朱振东,袁润逸,沙菁㛃,陈云飞。一种编码式纳米机器及其控制、制备方法。发明专利:ZL202110700953.920221014日。(授权)

5.    沙菁㛃,刘巍,司伟,徐伟。DNA多足纳米移动装置及其驱动方法。发明专利:ZL202110270618.X20220628日。(授权)

6.    司伟,孙倩怡,陈畅,余梦,沙菁㛃,章寅,陈云飞。一种超灵敏塑胶炸弹侦测传感器。发明专利:ZL201911214153.520220304日。(授权)

7.    司伟,陈畅,孙倩怡,余梦,沙菁㛃,章寅,陈云飞。多自由度自组装纳米机器人及其制作控制方法。发明专利:ZL201911214317.42022517日。(授权)

8.    章寅,赵佳斌,董隽,陈云飞,司伟,沙菁㛃。一种外泌体内肿瘤标志miRNA的分离和检测系统及方法。发明专利:ZL201910064022.72022。(授权)

9.    沙菁㛃,张志诚,陈云飞,傅方舟,孙倩怡,司伟,章寅。一种基于激光诱导空化的纳尺度薄膜孔制备装置及其方法。发明专利:ZL201910270000.62021。(授权)

10.  沙菁㛃,孙倩怡,张志诚,傅方舟,陈云飞,司伟,章寅。一种光控纳米孔的单分子可控输出装置及其使用方法。发明专利:ZL201811186463.62020。(授权)

11.  沙菁㛃,张志诚,陈云飞,孙倩怡,傅方舟,司伟,章寅。纳米孔检测芯片的便携式装夹装置。发明专利:ZL201811328020.62019。(授权)

12.  陈云飞,司伟,伍根生,章寅,沙菁㛃,刘磊。一种多通道阵列式DNA测序系统及其测序方法。发明专利:ZL201410320550.12016。(授权)

13.  陈云飞,倪振华,邹益人,袁志山,赵伟玮,伍根生,徐伟,司伟,沙菁洁,刘磊。一种可控的二维材料柔性转移方法.发明专利:2015.5.28, ZL201510331341.12016。(授权)

14.  陈云飞,司伟,沙菁㛃,刘磊. 一种基于纳米孔和原子力显微镜的三通道并行DNA测序传感器及检测方法.发明专利:ZL201410084787.42015。(授权)

申请发明专利:

15.  司伟陈皓男陈云飞一种基于纳米管和磁珠的生物传感器及其制备方法和应用。202411271207.2,20241122日。(申请)

16.  司伟,何军舟。一种多壁碳纳米管的生物传感器及其制备方法与应用。发明专利:202411124761.8, 20241108日。(申请)

17.  司伟,陈皓男,沙菁㛃,陈云飞。一种纳米管嵌套钻机治疗装置及其控制、制备方法。发明专利:202310280299.X, 20230728日。(申请)

18.  吴金明,李天慧,司伟。利用曲柄滑块实现自转轴系无滑环输电的公转自转机构。发明专利:202410834059.4,20241015日。(申请)

19.  蔡路,司伟。一种基于纳米摩擦发电的转速传感器。发明专利:202310977665.7, 20230804日。(申请)

20.  司伟,张震,沙菁㛃,陈云飞。复合纳米孔生物传感器及其制备方法与应用。发明专利:202310303255.420230327日。(申请)

21.  沙菁㛃,马超凡,司伟,陈云飞,徐伟,刘巍,徐昌晖。一种电渗流驱动的纳米马达结构。发明专利:202310159496.62023。(申请)

22.  司伟,王立伟,沙菁㛃,陈云飞。一种纳米管嵌套伸缩式治疗装置及其控制、制备方法。发明专利:202210354772.X20220406日。(申请)


Refereed Journals
Other Professional Activities
Selected Publications
Research Projects
Patents and Applications