题目: From Microfluidic Cell Culture to Organs on A Chip
报告人: Prof. Deyu Li
时间: 2013年12月18日,星期三, 10:00 am
地点: 院南高厅
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报告:From Microfluidic Cell Culture to Organs on A Chip
Microfluidic cell culture and co-culture represent a promising field that microfluidics can make a revolutionary impact to cell biology. In this talk, I will discuss
our research on several microfluidic platforms that enable new assays in cell biology studies. First, I will present a class of microfluidic valve-enabled cell
co-culture platforms. Through manipulating media exchange between cell populations, the platform enables novel assays to observe the dynamic process
of synapse formation in the central nervous system, to dissect the function of glia cells in neuronal activities, and to probe specific molecules in tumor
angiogenesis and metastasis. Next, I will discuss the effects of mechanical stress in normal tissue-fibroblast activation and genesis of cancer associated
fibroblasts. The important mechanotransduction mechanism might play a critical role in tumor progression. The last topic will be some new progress in
culturing whole organ, retina, on a chip.
报告人: Prof. Deyu Li
Bio. Deyu Li received his B.S., M.E., and Ph.D. degrees from the University of Science and Technology of China, Tsinghua University, and the University
of California, Berkeley, respectively. He joined Vanderbilt University in 2004 as assistant professor in the Department of Mechanical Engineering and was
promoted to associate professor in 2010. His research interest includes nanoscale thermal transport and micro/nanofluidics. He has published 50 journal
papers, which have been cited over 3200 times. He received an NSF career award in 2007, Vanderbilt Chancellor’s Award for Research in 2013, and his
research has also won best poster awards in MRS and IMECE.